Bioactive Small Molecules
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Filtered Search Results
Selleck Chemical LLC Loganic acid S9191-1MG
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Loganic acid (Loganate) is a naturally occurring iridoid monoterpeneglusoside involved in the biosynthesis of indole alkaloids in Vinca rosea
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Selleck Chemical LLC Shanzhiside methyl ester S9307-1MG
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Shanzhiside methylester is a principle effective iridoid glycoside of L rotata and serves as a small molecule glucagon-like peptide-1 (GLP-1) receptor agonist
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Selleck Chemical LLC Belvarafenib S8853-10MM/1ML
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Belvarafenib is a selective and orally bioavailable pan-RAF kinase inhibitor with IC50 values of 41 nM 7 nM and 2 nM for BRAF WT BRAF(V600E) and CRAF kinases respectively
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Selleck Chemical LLC GSK3368715 3HCl S8858-10MM/1ML
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GSK3368715 3HCl is a potent inhibitor of type I protein arginine methyltransferases (PRMT) that inhibits PRMT1 3 4 6 and 8 with Kiapp vaules ranging from 1 5 to 81 nM
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Selleck Chemical LLC Blinin S9481-2MG
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Blinin isolated from the whole plant of Conyza blinii is used in folk medicine in the south-west of China
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Cayman Chemical ANTIBODY NIthIamIde 5g
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An antiprotozoal agent; active against G. intestinalis and T. vaginalis (IC50s = 0.49 and 0.022 µM, respectively); reduces mortality in a turkey model of histomoniasis at 0.05% in the diet
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Medchemexpress LLC Poseltinib | 1353552-97-2 | 98.1% | 470.52 | 1 ML
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Poseltinib is an orally active, selective, irreversible small molecule Bruton tyrosine kinase (BTK) inhibitor with an IC50 of 1.95 nM. It effectively inhibits signaling mediated by B cell receptors (BCR), Fc receptors (FcR), and Toll-like receptors (TLR). Poseltinib also exhibits anti-inflammatory activity and is being researched for rheumatoid arthritis.
- Orally active, selective, irreversible small molecule Bruton tyrosine kinase (BTK) inhibitor.
- Effectively inhibits signaling mediated by B cell receptors (BCR), Fc receptors (FcR), and Toll-like receptors (TLR).
- Exhibits anti-inflammatory activity.
- Potential for research in rheumatoid arthritis.
- Appearance: solid, light yellow to yellow.
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Cayman Chemical C18 CeramIded18 118 0 5mg
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A bioactive sphingolipid; the primary short-chain ceramide found in brain tissue; synthesis is regulated by Lass1 in mice; positively correlated to body mass index and inversely related to insulin sensitivity; reduces cell growth in UM-SCC-22A squamous cell carcinoma cells; selectively downregulated in 32 squamous cell carcinoma tumor tissues; positively correlated to body mass index and inversely related to insulin sensitivity in type 2 diabetic patients
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Selleck Chemical LLC Coffee fruit Extract E3380-5MG
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Coffee Fruit Extract is extrcated from the fruits of Coffea which improves brain-derived neurotrophic factor (BDNF) cognitive function and mood of older adults
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Selleck Chemical LLC Ingliforib S0031-25MG
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Ingliforib (CP 368296) is a glycogen phosphorylase (GP) inhibitor with IC50s of 52 352 and 150 nM for liver muscle and brain glycogen phosphorylase and has cardioprotective activity
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Selleck Chemical LLC Sophora flavescensExtract E3387-5MG
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Sophora Flavescens Extract is extracted from Sophora flavescens which is used in the treatment of ulcerative colitis with damp-heat accumulation syndrome
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Selleck Chemical LLC ABX464 S0076-25MG
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ABX464 (SPL-464) is a novel anti-HIV molecule that inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) from 5 different donors with IC50 ranging between 0 1 M and 0 5 M
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Selleck Chemical LLC Jujubae Fructus Extract E3131-5MG
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Jujubae Fructus Extract is extracted from fruit of Ziziphus jujuba Mill which provides an effective treatment for chronic constipation and type 2 diabetes
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Cayman Chemical ANTIBODY 93-O17S 50mg
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An ionizable cationic lipidoid; has been used in the synthesis of lipid nanoparticles for the delivery of Cre recombinase and ribonucleoproteins for genome editing in mice; LNPs containing 93-O17S have been used for the intratumoral delivery of cGAMP to enhance cross-presentation of tumor antigens and STING activation in a B16/F10 murine melanoma model
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Selleck Chemical LLC AF-353 S0405-1G
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AF-353 (Ro-4) is a potent selective and orally bioavailable antagonist of P2X3 receptor and P2X2/3 receptor with pIC50 of 8 06 8 05 and 7 41 for human P2X3 rat P2X3 and human P2X2/3 respectively
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